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What is procaine?

What is procaine?

Procaine (English: Procaine), its trade name Novocaine (English: Novocaine), a local anesthetic. Originally used to relieve pain caused by intramuscular injection of penicillin, procaine is also used in dental surgery. The main function is sodium channel blocker .
Procaine was first synthesized in 1905 by the German chemist Alfred Einhorn, somewhat later than amelocaine . Alfred Einhorn's trade name was Novacaine, based on Latin. (Nova- means "new," and -caine is a common end-of-word for narcotic alkaloids. It was introduced into clinical use by surgeon Heinrich Braun, and before the advent of stovaine and procaine, cocaine was the most commonly used local anesthetic

1.What is procaine used for?

2.What is procaine hydrochloride?

3.What is procaine made from?

4.Where is procaine absorbed?

 

1.What is procaine used for?

Local anesthetics are the main use of procaine. Due to the advent of lidocaine, a more powerful local anesthetic, it is no longer in common use and procaine has been withdrawn from the US market. Like other local anesthetics such as Mepivacaine and Prilocaine, procaine is a vasodilator and is ofteWhat is procaine hydrochloride?

2.What is procaine hydrochloride?

Procaine hydrochloride, also called Novocain, or Novocaine, synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name Novocaine, it became the first and best-known substitute for cocaine in local anesthesia.

3.What is procaine made from?

Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

4.Where is procaine absorbed?

Procaine is an ester anesthetic. It is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-aminobenzoic acid (PABA), which is then excreted by the kidneys into the urine.

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